MALIGNANT INTESTINAL SCHWANNOMA - A CASE-REPORT AND A REVIEW OF THE LITERATURE IN JAPAN

We report the rare case of malignant intestinal schwannoma, not accomp anied with von Recklinghausen's disease, The main tumor was located in the ileum with multiple small tumors observed on the peritoneum. Hist ologically the tumor was composed of spindle cells exhibiting a nuclea r palisading formation and abnormal mitotic figures were observed, The tumor was immunohistochemically positive for S-100 protein, glial fib rillary acidic protein, vimentin and neuron-specific enolase, but nega tive for desmin, Electron microscopically the tumor cell exhibited mor phological findings characteristic of sch schwann cell differentiation . On the basis of these results, the tumor was diagnosed as malignant schwannoma occurring in the ileum.