C. Dufau et al., UNEXPECTED BREAKDOWN OF A P-C BOND WHEN A TTEMPTING TO SYNTHESIZE THECADMIUM SALT OF ALENDRONATE (4-AMINO 1-HYDROXY BUTYLIDENE 1,1-BISPHOSPHONIC ACID), Comptes rendus de l'Academie des sciences. Serie II. Mecanique, physique, chimie, astronomie, 321(11), 1995, pp. 471-474
Whereas HEBP (etidronate) gives with cadmium carbonate a well crystall
ized salt whose crystal structure is known, alendronate gives in the s
ame experimental conditions a crystalline compound, where no cadmium i
s found. It is the Bis-2,2' (dihydroxy phosphinoyl)-N (2',3'4',-H pyrr
olyl) pyrrolidine.