DETERMINATION OF FOSINOPRIL IN PHARMACEUTICAL FORMULATIONS CONTAININGHYDROCHLOROTHIAZIDE BY MULTIWAVELENGTH UV SPECTROPHOTOMETRY

Authors
MAGRI AL FABRIZIO BB MAGRI AD MARINI D
Citation
Al. Magri et al., DETERMINATION OF FOSINOPRIL IN PHARMACEUTICAL FORMULATIONS CONTAININGHYDROCHLOROTHIAZIDE BY MULTIWAVELENGTH UV SPECTROPHOTOMETRY, Talanta, 42(11), 1995, pp. 1719-1723
Citations number
8
Journal title
Talanta
ISSN journal
00399140 → ACNP
Volume
42
Issue
11
Year of publication
1995
Pages
1719 - 1723
Database
ISI
SICI code
0039-9140(1995)42:11<1719:DOFIPF>2.0.ZU;2-A
Abstract
A sensitive, simple, rapid and precise method for the simultaneous det ermination of fosinopril (FOS) and hydrochlorothiazide (HCT) in pharma ceutical formulations is presented. These active ingredients are extra cted in aqueous solution and measured by multiwavelength UV spectropho tometry using the program QUEST. HCT acts as an internal standard to v erify the accuracy of the analysis. Some aspects of the chemical, spec troscopic and thermoanalytical behaviour of FOS are also reported.