Jkt. Lee et al., DETERMINATION OF SERUM CREATININE LEVEL BEFORE INTRAVENOUS ADMINISTRATION OF IODINATED CONTRAST-MEDIUM - A SURVEY, Investigative radiology, 30(12), 1995, pp. 700-705
RATIONALE AND OBJECTIVES. To study the practice of obtaining serum cre
atinine before administering intravenous iodinated contrast medium and
the costs associated with this practice. MATERIALS AND METHODS. In Ju
ne 1993, a questionnaire was sent to 217 physicians who are members of
the Society of Uroradiology or the Society of Computed Body Tomograph
y/Magnetic Resonance. There were 149 respondents who completed a total
of 70 questionnaires, providing a response rate of 69% (149/217). RES
ULTS. The percentage of institutions that always require a serum creat
inine before administering intravenous contrast medium for excretory u
rography, body computed tomography, and head computed tomography was 1
3%, 20%, and 14%, respectively, In institutions where routine serum cr
eatinine is not required, approximately 60% request a serum creatinine
in either insulin-dependent or juvenile type 1 diabetes. The mean max
imal acceptable time between the serum creatinine value and contrast a
dministration is 29 days. It takes a mean of 69 minutes to get the res
ults of a stat serum creatinine and costs a mean of 15 dollars for the
test, In patients with no risk factors, the mean for the highest seru
m creatinine value at which respondents still gave contrast was 2.1 mg
/dL; in patients with risk factors, the mean was 1.9 mg/dL. There was
no correlation between the use of serum creatinine and the number of s
tudies performed in the institution or the type of contrast used. CONC
LUSIONS. The practice of requiring a pretest serum creatinine and its
interpretation regarding the use of contrast media are quite variable.
In view of this disparity in opinion, development and acceptance of a
list of patients who are at increased risk for contrast-induced nephr
opathy may be desirable.