The evidence that PCBs are involved in eggshell thinning is examined.
In experiments in which both PCBs and DDE were used, it was found that
DDE, but not PCBs, caused eggshell thinning of mallard and American k
estrel. For two other species, bobwhite and Japanese quail, no thinnin
g was observed with either agent. Numerous other studies with DDE alon
e have demonstrated that this agent can cause eggshell thinning in man
y, but not all, species. It is concluded that DDE is the only compound
that has caused significant eggshell thinning at environmentally real
istic doses.