Ec. Madu et al., CLINICAL UTILITY OF DIGITAL DOBUTAMINE STRESS ECHOCARDIOGRAPHY IN THENONINVASIVE EVALUATION OF CORONARY-ARTERY DISEASE, Archives of internal medicine, 154(10), 1994, pp. 1065-1072
Exercise electrocardiography is an established mode of evaluation for
patients with suspected coronary artery disease. It also provides prog
nostic information and guides therapeutic management in patients with
established disease. However, some patients are unable to exercise bec
ause of orthopedic problems, neurologic diseases, peripheral vascular
disease, or deconditioning. In the past, these patients have been refe
rred for angiography to help assess their disease. Recently, however,
new techniques to assess myocardial perfusion and/or function, includi
ng stress echocardiography, have been used in the noninvasive assessme
nt of coronary artery disease in this group of patients. Echocardiogra
phy has been used in combination with different drugs, including dobut
amine, dipyridamole, and adenosine. Dobutamine is probably the single
most studied drug for stress echocardiography. Dobutamine stress echoc
ardiography is a safe, feasible, and valuable technique for evaluating
coronary artery disease.