PREPARATION OF NOVEL REDOX COPOLYMERS - POLY[FERROCENYLMETHYL METHACRYLATE-CO-METHOXY-OLIGO(ETHYLENE OXIDE) METHACRYLATE], AND THEIR USE ASPOLYMERIC MEDIATORS IN AMPEROMETRIC GLUCOSE SENSORS

A series of novel, copolymers: poly[ferrocenylmelthyl methacrylate-co- methoxy-oligo(ethylene oxide) methacrylate], have been prepared by rad ical copolymerization and characterized. These copolymers have been ut ilized as polymeric mediators for amperometric glucose sensors. Glucos e oxidase (GOD) and the redox copolymers were mixed with carbon paste, and carbon paste GOD electrodes were prepared to amperometrically det ect concentrations of glucose. From cyclic voltammetry measurements us ing the carbon paste electrodes in the absence and presence of glucose , these copolymers were proved to function as polymeric mediators betw een the redox center of GOD and the electrode. The mediation current r esponse was highly sensitive and increased with increasing glucose con centrations up to 50 mM. Composition of the redox copolymers incorpora ted in the carbon paste electrodes also influenced the current respons e.