INVESTIGATION OF CYCLODEXTRIN INCLUSION-COMPOUNDS USING FT-IR AND RAMAN-SPECTROSCOPY

The investigation by FT-IR and Raman spectroscopy of several cyclodext rin inclusion complexes reveals structural features not readily access ible by other spectroscopic methods. Thus, the cis conformation of ter ephthalaldehyde dominates within the alpha-cyclodextrin cavity. The lo cked and unlocked acetate group of hydroquinone diacetate in beta-cycl odextrin can be easily distinguished, while p-benzenedimethanol diacet ate displays the features of a ''solid solution''. Finally, the detect ion of hydrogen bonding in the alpha-cyclodextrin inclusion compound o f butanediol diacetate brings to light even more complex supramolecula r structures.