Am. Polson et al., PERIODONTAL HEALING AFTER GUIDED TISSUE REGENERATION WITH ATRISORB BARRIERS IN BEAGLE DOGS, The International journal of periodontics & restorative dentistry, 15(6), 1995, pp. 575-589
Periodontal healing after use of Atrisorb barrier material (polylactic
acid) for guided tissue regeneration was studied in the premolar and
molar teeth of six beagle dogs. Defects studied were surgically induce
d or were caused by naturally occurring periodontitis. Barriers fragme
nted and became displaced in 2 to 5 weeks after application. Granulati
on tissue was sometimes present between the barrier and roof surface a
t 10 days to 4 weeks. Several sites were surgically reentered at 4 mon
ths, and new bone covered 60% to 100% of the formerly exposed furcatio
ns and root surfaces. sites obtained for histologic evaluation 9 to 12
months after the baseline surgery showed new connective tissue attach
ment cementum, and alveolar bone. Histomorphometric analyses quantitat
ed these tissue changes, and new connective tissue attachment covered
72% of surgically exposed root surfaces and 77% of periodontitis-expos
ed root surfaces. it was concluded that new periodontal supporting tis
sues became reconstituted on root and furcation surfaces after use of
the Atrisorb barrier material for GTR.