ISOLATION AND CRYSTAL-STRUCTURE OF STYLOPEPTIDE-1, A NEW MARINE PORIFERA CYCLOHEPTAPEPTIDE

Citation
Gr. Pettit et al., ISOLATION AND CRYSTAL-STRUCTURE OF STYLOPEPTIDE-1, A NEW MARINE PORIFERA CYCLOHEPTAPEPTIDE, Journal of organic chemistry, 60(25), 1995, pp. 8257-8261
Citations number
35
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
00223263
Volume
60
Issue
25
Year of publication
1995
Pages
8257 - 8261
Database
ISI
SICI code
0022-3263(1995)60:25<8257:IACOSA>2.0.ZU;2-V
Abstract
Stylopeptide 1 (1) was isolated respectively from the South and Wester n Pacific Ocean sponges Stylotella sp. and Phakellia costata. Structur al determination was accomplished by utilizing high-field (500 MHz) 2D -NMR experiments and confirmed by an X-ray crystal structure determina tion to provide the assignment cyclo(Pro-Leu-Ile-Phe-Ser-Pro-Ile). The absolute configuration of the new cycloheptapeptide was established b y employing results of chiral gas chromatographic analyses.