CATALYTIC ASYMMETRIC IODOCARBOCYCLIZATION REACTION

Authors
INOUE T KITAGAWA O OCHIAI O SHIRO M TAGUCHI T
Citation
T. Inoue et al., CATALYTIC ASYMMETRIC IODOCARBOCYCLIZATION REACTION, Tetrahedron letters, 36(51), 1995, pp. 9333-9336
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
51
Year of publication
1995
Pages
9333 - 9336
Database
ISI
SICI code
0040-4039(1995)36:51<9333:CAIR>2.0.ZU;2-U
Abstract
The iodocarbocyclization reactions of 4-pentenylmalonate derivatives u sing 20 mol% of the chiral titamium complex in the presence of 12 and 2,6-dimethoxypyridine proceeded with high enantioselectivity to give g ood yields of cyclopentane cyclopentone derivatives. The origin of ena ntioselectivity in the present reaction is discussed on the basis of X -ray crystal structural data of the chiral titanium complex from acety lacetone, chiral diol and Ti(IV).