DETECTION OF LOW-GRADE MOSAICISM IN FETAL CELLS ISOLATED FROM MATERNAL BLOOD

Authors
BISCHOFF FZ LEWIS DE SIMPSON JL NGUYEN DD SCOTT J SCHOBER W MURRELL S ELIAS S
Citation
Fz. Bischoff et al., DETECTION OF LOW-GRADE MOSAICISM IN FETAL CELLS ISOLATED FROM MATERNAL BLOOD, Prenatal diagnosis, 15(12), 1995, pp. 1182-1184
Citations number
4
Categorie Soggetti
Obsetric & Gynecology
Journal title
Prenatal diagnosis → ACNP
ISSN journal
01973851
Volume
15
Issue
12
Year of publication
1995
Pages
1182 - 1184
Database
ISI
SICI code
0197-3851(1995)15:12<1182:DOLMIF>2.0.ZU;2-Z
Abstract
Recovering and analysing fetal erythrocytes from maternal blood is bei ng pursued for non-invasive prenatal genetic diagnosis. We report the observation of 46,XY/47,XXY mosaicism in fetal cells from a woman whos e first-trimester chorionic villus sampling (CVS) initially showed onl y 46,XY. Only after exhaustive (500 cells) analysis were four XXY cell s found in cultured villi.