Cf. Serago et al., COMPARISON OF PROTON AND X-RAY CONFORMAL DOSE DISTRIBUTIONS FOR RADIOSURGERY APPLICATIONS, Medical physics, 22(12), 1995, pp. 2111-2116
Highly focused dose distributions for radiosurgery applications are su
ccessfully achieved using either multiple static high-energy particle
beams or multiple-are circular x-ray beams from a linac. It has been s
uggested that conformal x-ray techniques using dynamically shaped beam
s with a moving radiation source would offer advantages compared to th
e use of only circular beams. It is also thought that, generally, char
ged particle beams such as protons offer dose deposition advantages co
mpared to x-ray beams. A comparison of dose distributions was made bet
ween a small number of discrete proton beams, multiple-are circular x-
ray beams, and conformal x-ray techniques. Treatment planning of a sel
ection of radiosurgery cases was done for these three techniques. Targ
et volumes ranged from 1.0-25.0 cm(3). Dose distributions and dose vol
ume histograms of the target and surrounding normal brain were calcula
ted. The advantages and limitations of each technique were primarily d
ependent upon the shape and size of the target volume. In general, pro
ton dose distributions were superior to x-ray distributions; both shap
ed proton and shaped x-ray beams delivered dose distributions which we
re more conformal than x-ray techniques using circular beams; and the
differences between all proton and x-ray distributions were negligible
for the smallest target volumes, and greatest for the larger target v
olumes.