In this review an account of the numerous works related to the determi
nation of the conformation in solution of thiophenic compounds is give
n. Most of the studies were effected by dipole moment measurement, inf
rared and microwave absorption, or theoretical calculations. NMR spect
rometry was employed as a priviledged tool in many cases, using the me
asurements of the stereospecific coupling constants across five bonds,
An interpretation of the results is proposed.