STUDY OF A POLYMER IMMOBILIZED ON SILICA-GEL AS STATIONARY-PHASE FOR CHIRAL LIQUID-CHROMATOGRAPHY

Authors
GUILLAUME M SEBILLE B
Citation
M. Guillaume et B. Sebille, STUDY OF A POLYMER IMMOBILIZED ON SILICA-GEL AS STATIONARY-PHASE FOR CHIRAL LIQUID-CHROMATOGRAPHY, European Polymer Journal, 32(1), 1996, pp. 19-26
Citations number
36
Categorie Soggetti
Polymer Sciences
Journal title
European Polymer Journal → ACNP
ISSN journal
00143057
Volume
32
Issue
1
Year of publication
1996
Pages
19 - 26
Database
ISI
SICI code
0014-3057(1996)32:1<19:SOAPIO>2.0.ZU;2-G
Abstract
The adsorption of beta-cyclodextrin polymer was studied on different s ilica beads, in water-organic solvent mixtures. A maximum adsorption o n Lichrospher 100 Angstrom 5 mu m was observed for a polymer solution containing 70% acetone. Different crosslinking agents were used to sta bilize the polymer layer on the silica surface to make a convenient su pport for liquid chromatography. Glutaraldehyde appeared as very effic ient for this purpose and enabled chiral supports to be prepared.