RIBOSOMAL-PROTEINS AND ELONGATION-FACTORS

Authors
LILJAS A GARBER M
Citation
A. Liljas et M. Garber, RIBOSOMAL-PROTEINS AND ELONGATION-FACTORS, Current opinion in structural biology, 5(6), 1995, pp. 721-727
Citations number
59
Categorie Soggetti
Cell Biology",Biology
Journal title
Current opinion in structural biology → ACNP
ISSN journal
0959440X
Volume
5
Issue
6
Year of publication
1995
Pages
721 - 727
Database
ISI
SICI code
0959-440X(1995)5:6<721:RAE>2.0.ZU;2-3
Abstract
Structural work on the translation machinery has recently undergone ra pid progress. It is now known that six out of nine ribosomal proteins have an RNA-binding fold, and two domains of elongation factors Tu and G have very similar folds. in addition, the complex of EF-Tu with a G TP analogue and Phe-tRNA(Phe) has a structure that overlaps exceedingl y well with that of EF-G GDP. These findings obviously have functional implications.