A 15-year-old girl was diagnosed as having acute nonlymphocytic leukem
ia (ANLL, FAB M2) in January 1990 and achieved complete remission with
chemotherapy. She was readmitted to our hospital with a hearing distu
rbance and hoarseness in October 1990. A suprapharyngeal tumor was fou
nd on cranial MRI, and bone marrow leukemic cells were slightly increa
sed in number. Involvement of leukemic cells was proven by biopsy of t
he tumor, Therefore, we made a diagnosis of ANLL relapse with Garcin's
syndrome. To our knowledge, this is the first reported case of leukem
ia complicated by Garcin's syndrome.