Tz. Oconnor et al., MEASUREMENT OF EXPOSURE TO ENVIRONMENTAL TOBACCO-SMOKE IN PREGNANT-WOMEN, American journal of epidemiology, 142(12), 1995, pp. 1315-1321
The authors compared three methods used to measure exposure to environ
mental tobacco smoke in pregnant women: personal air monitor, urine co
tinine, and questionnaire. Environmental tobacco smoke exposure assess
ment methods were compared for agreement using Cohen's Kappa and the S
pearman rank order correlation coefficient. Women who reported exposur
e had significantly higher levels of air nicotine concentration compar
ed with women who reported no exposure, but urine cotinine did not dif
fer. Air nicotine was, more highly correlated with home exposure (r =
0.34) than work exposure (r = 0.18). Urine cotinine correlated with wo
rk exposure (r = 0.14) but neither home nor social exposure. Agreement
was ''fair'' (Kappa = 0.29) when self-reported exposure was compared
with air monitor, but agreement was ''poor'' when urine cotinine was c
ompared with serf-report (Kappa = 0.08) and air monitor (Kappa = 0.10)
. In low environmental tobacco smoke exposure environments, all three
methods for measuring exposure may have a role, although modification
to monitoring protocols will be needed to improve monitoring sensitivi
ty and exposure classification.