COMPLICATIONS AFTER TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA IN WOMEN INFECTED WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS

OBJECTIVE: To compare the frequency of complications after treatment o f cervical intraepithelial neoplasia (CIN) in human immunodeficiency v irus (HIV)-infected and -seronegative women in an ambulatory setting. STUDY DESIGN: A retrospective record review of 15 HIV-infected and 44 HIV-negative women treated by laser therapy or cone biopsy and retrosp ective interviews of 20 HIV-infected and 44 HIV-negative women treated by cryotherapy. RESULTS: Four of 35 (11%) HIV-infected women had exce ssive bleeding after laser/cone or cryotherapy as compared to one of 8 8 (1%) HIV-negative women (odds ratio 11.27, P=.02). After laser/cone therapy, significantly move HIV-infected women (53%) had cervicovagina l infections than did HIV-negative women (18%). A higher prevalence of infection tons associated with move severe immunodeficiency. CONCLUSI ON: HIV-infected women are vulnerable to complications after treatment of CIN and should be monitored closely.