MULTICORE MYOPATHY ASSOCIATED WITH MULTIPLE PTERYGIUM SYNDROME AND HYPERTROPHIC CARDIOMYOPATHY

A boy with multicore myopathy associated with multiple pterygium syndr ome and hypertrophic cardiomyopathy is described. Light microscopy of biopsy samples from the skeletal muscle and myocardium revealed multip le cores in the muscle fibers in the former but their absence in the l atter. These results suggest that the pathogenesis of the histologic c hanges might differ between skeletal muscle and myocardium, and that f urther electron microscopic examination be done on both types of speci men. The prognosis of multicore myopathy is not usually good when card iac involvement is present.