DESIGN AND PERFORMANCE OF A HIGH-RESOLUTION ELECTROSPRAY ION-SOURCE FOR A MAGNETIC-SECTOR MASS-SPECTROMETER WITH A HEATED CAPILLARY INLET

Authors
JIANG LF MOINI M
Citation
Lf. Jiang et M. Moini, DESIGN AND PERFORMANCE OF A HIGH-RESOLUTION ELECTROSPRAY ION-SOURCE FOR A MAGNETIC-SECTOR MASS-SPECTROMETER WITH A HEATED CAPILLARY INLET, Journal of the American Society for Mass Spectrometry, 6(12), 1995, pp. 1256-1261
Citations number
18
Categorie Soggetti
Chemistry Physical","Chemistry Analytical",Spectroscopy
Journal title
Journal of the American Society for Mass Spectrometry → ACNP
ISSN journal
10440305
Volume
6
Issue
12
Year of publication
1995
Pages
1256 - 1261
Database
ISI
SICI code
1044-0305(1995)6:12<1256:DAPOAH>2.0.ZU;2-Y
Abstract
The design and performance of an electrospray ion source for a high re solution magnetic sector mass spectrometer that utilizes a heated capi llary has been presented. Low pressure, high sensitivity, stable elect rospray, low flow rates, and low electronic noise were important facto rs in achieving high resolution electrospray mass spectrometry. A unit mass resolution has been achieved for biomolecules with MW > 12,000, and an accuracy of 1.4 ppm has been achieved for the average molecular weight of bovine insulin.