We analyze in detail the possible breaking of space-time supersymmetry
under T-duality transformations. We find that when appropriate world-
sheet effects are taken into account apparent puzzles concerning super
symmetry in space-time are solved. We study T-duality in general heter
otic sigma-models analyzing possible anomalies, and we find some modif
ications of Buscher's rules. We then work out a simple but representat
ive example which contains most of the difficulties. We also consider
the issue of supersymmetry versus duality for marginal deformations of
WZW models and present a mechanism that restores supersymmetry dynami
cally in the effective theory.