Le. Probst et al., DIAGNOSIS OF CONGENITAL-SYPHILIS IN ADULTS PRESENTING WITH INTERSTITIAL KERATITIS, Canadian journal of ophthalmology, 29(2), 1994, pp. 77-80
In the antibiotic era the ophthalmologist has become less familiar wit
h the diagnosis of congenital syphilis. The recognition of this diseas
e is crucial, as neurosyphilis or cardiovascular syphilis will develop
in a substantial number of patients with latent congenital syphilis w
ithout the appropriate treatment. We describe eight patients aged 60 y
ears or more who presented with refractive problems in whom cogneital
syphilis was subsequently diagnosed for the first time. One patient wa
s found to have neurosyphilis and the highest VDRL result ever recorde
d by the London Public Health Laboratory. Seven patients required exte
nsive antibiotic therapy, an three subsequently underwent successful o
cular surgery. These cases illustrate the importance of recognizing th
is treatable disease.