CONTINUATION OF A DONOR OOCYTE PREGNANCY IN A FUNCTIONALLY AGONADAL PATIENT WITHOUT EARLY ESTROGEN SUPPORT

A 40 year old functionally agonadal patient was the recipient of ferti lized donated oocytes. She accidentally discontinued all oestrogen sup port on the day preceding embryo transfer until it was reinstated 12 d ays later. However, a pregnancy was established and resulted in the bi rth of healthy normal twin infants. This case report suggests that min imal amounts, if any, of oestradiol are sufficient to maintain an earl y pregnancy, provided adequate amounts of progesterone are given. This is consistent with a recent study conducted in subhuman primates.