Background. We examined whether expressed emotion (EE) influenced the
course of schizophrenia in Japan. Method. We conducted a cohort study.
Of 73 subjects with schizophrenia meeting the diagnostic criteria of
ICD-9 or DSM-III-R, 52 participated in the study. The Camberwell Famil
y interview was conducted to evaluate EE. The subjects had been follow
ed up for nine months and psychiatrists who were blind to the EE statu
s evaluated their symptoms with the Brief Psychiatric Rating Scale. Re
sults. The relapse rate in the high-EE group was 58% and that in the l
ow-EE group 21% (P<0.01). Nine-month relapse risk ratio was 2.72 (95%
Cl 1.24 to 5.97). Conclusion. In Japan, as elsewhere, EE is a good pre
dictor of schizophrenic relapse.