Purpose: The authors studied the effectiveness of laserpexy versus cry
opexy for treatment of acute retinopathy of prematurity. Methods: Seve
nty-six eyes in 41 patients were treated for acute retinopathy of prem
aturity from January 1998 to April 1994. Results: Fifty-six eyes in 30
patients had zone 2 disease. Of these 30 patients, 11 received laser
treatment and 20 received cryopexy treatment; there was at least one a
natomically successful eye in each patient. Twenty eyes in ten patient
s had zone 1 disease. Seven patients had bilateral laser treatment. Th
ree patients had bilateral cryopexy. In seven eyes with zone 1 disease
, five were treated successfully with laser. None of the three eyes wi
th zone 1 disease treated with cryopexy were successful. Conclusion: L
aserpexy and cryopexy are of equal efficacy in treating zone 2 disease
. There is a tendency that suggests that laserpexy is more effective t
han cryopexy in treating zone 1 disease. Diode and argon lasers are of
equal efficacy in treating zone 1 disease.