Miconazole nitrate 2% was tested for its efficacy against Microsporum
gallinae (the causative agent in favus) in a nock of various Oriental
breed (Shame and Aseel) and crossbreed chickens. Six adult males showi
ng clinical signs of favus were randomized into control and experiment
al groups. The males were maintained on individual tiecords on the ran
ge, with no physical contact between birds. The experimental birds had
the affected areas washed with soap and water and dried, and an ointm
ent of miconazole nitrate 2% was applied. The experimental birds recei
ved the treatment twice a day for 34 days. Scrapings from the affected
areas of all birds were cultured at the beginning and end of the test
. Ar the end of the treatment period, the control birds were still pos
itive for M. gallinae, but the organism could not be cultured from the
treated birds.