ENANTIOSPECIFIC SYNTHESIS OF CARBOCYCLIC AMINOIMIDAZOLE CARBOXAMIDE RIBONUCLEOTIDE (C-AICAR), SUCCINOAMINOIMIDAZOLE CARBOXAMIDE RIBONUCLEOTIDE (C-SAICAR), AND A NEW INTERMEDIATE FOR SAICAR ANALOGS
L. Schmitt et Ca. Caperelli, ENANTIOSPECIFIC SYNTHESIS OF CARBOCYCLIC AMINOIMIDAZOLE CARBOXAMIDE RIBONUCLEOTIDE (C-AICAR), SUCCINOAMINOIMIDAZOLE CARBOXAMIDE RIBONUCLEOTIDE (C-SAICAR), AND A NEW INTERMEDIATE FOR SAICAR ANALOGS, Nucleosides & nucleotides, 14(9-10), 1995, pp. 1929-1945
The (-)-enantiomer of the carbocyclic analogs of aminoimidazole carbox
amide ribonucleotide (C-AlCAR(1), 7), and succinoaminoimidazole carbox
amide ribonucleotide (C-SAlCAR, 14) have been prepared. En route, a ne
w intermediate (19) for the preparation of SAlCAR analogs was develope
d.