The gene encoding human transcription factor E4TF1-60 was previously m
apped to chromosome 21q21. We analyzed the localization of the E4TF1-6
0 gene in more detail by genomic Southern hybridization and determined
the sequence of the exons and the regions surrounding the intron boun
daries. We report here that E4TF1-60 locates in the long arm of chromo
some 21 at q21.2-q21.3 and contains a total of ten exons.