DERIVATIVES OF NATURAL TETRAPYRROLES FOR PHOTODYNAMIC THERAPY .3. OXIDATIVE-DEGRADATION STUDIES ON PORPHYRINS WITH CHROMIC-ACID

Until now the composition of the complex porphyrin mixtures of hematop orphyrin derivative (HPD) and Photofrin II could not be clarified in d etail. We investigated the applicability of oxidative degradation to t he structural assignment of HPD constituents. Therefore, some fundamen tal work concerning the characterization of the relevant degradation p roducts had to be done. In this article we present the spectral and an alytical data of monomeric and dimeric maleimides potentially arising from the corresponding constituents of HPD.