Spinal epidural lipomatosis (SEL) is a rare complication of iatrogenic
Gushing's syndrome (CS). There is only one case reported of symptomat
ic SEL in association with endogenous CS. We present a patient with co
mpressive myeloradiculopathy due to SEL and Gushing's disease and sugg
est that in SEL of hypercortisolism, the excess of corticosteroids is
the stimulus for the growth of adipose tissue in the spinal canal and
that treatment should be aimed at correcting the endocrine abnormality
.