ISOXAZOLES AS LATENT ALPHA-CYANOALDEHYDES - CONSTRUCTION OF THE INDOLE[2,3-A]QUINOLIZINE RING-SYSTEM

Authors
PEREZ C JANIN YL GRIERSON DS
Citation
C. Perez et al., ISOXAZOLES AS LATENT ALPHA-CYANOALDEHYDES - CONSTRUCTION OF THE INDOLE[2,3-A]QUINOLIZINE RING-SYSTEM, Tetrahedron, 52(3), 1996, pp. 987-992
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
3
Year of publication
1996
Pages
987 - 992
Database
ISI
SICI code
0040-4020(1996)52:3<987:IALA-C>2.0.ZU;2-G
Abstract
A new access to the indolo[2,3-a]quinolizine ring system was devised u sing the thermal decarboxylative ring-opening of 3-carboxyl isoxazoles into alpha-cyano aldehydes. Thus, from acetal 8b the indolo[2,3-a]qui nolizine 5 was obtained in four steps via the beta-carboline 11 which on heating gave compound 5.