Pw. Kodituwakku et al., SPECIFIC IMPAIRMENTS IN SELF-REGULATION IN CHILDREN EXPOSED TO ALCOHOL PRENATALLY, Alcoholism, clinical and experimental research, 19(6), 1995, pp. 1558-1564
The present study utilizes a conceptual framework derived from theorie
s of cognition to explain the pattern of behavioral and learning probl
ems observed in subjects with fetal alcohol syndrome (FAS) and fetal a
lcohol effects (FAE). Based on a modern interpretation of Luria's theo
ry of self-regulation, this study used a neuropsychological test batte
ry to compare 10 subjects (mean age = 13 years) having FAS/FAE with 10
control subjects (mean age = 12 years and 9 months). Subjects with FA
S/FAE were relatively high functioning and did not significantly diffe
r from controls with respect to receptive vocabulary. However, those w
ith FAS/FAR exhibited greater difficulty than controls on tasks that i
nvolved the manipulation of information and goal management in working
memory (e.g., Planning, Controlled Oral Word Association, etc). Both
groups performed equally well on some tasks that demanded rule learnin
g (Delayed Response) and response inhibition (Go-No-Go). The above imp
airments were interpreted to be reflective of selective rather than ge
neralized disruptions of neural networks that subserve working memory.