The prevalence of respiratory disease in a Midwest Hispanic (mostly Me
xican) migrant from worker population was investigated Chronic respira
tory symptoms (cough, wheezing, sputum production) in adult workers (n
= 354) were elevated (8.5%, 6.2%, 6.5%, respectively) and were accomp
anied by physiologic abnormalities as determined by pulmonary function
testing. Over 15% of the adult cohort exhibited a FEV(1)/FVC < 75, an
d over 14% had FEF(25-75) values which were less than 60% of predicted
. The observed airflow obstruction of both large and small airways was
not explained by cigarette usage (43%) in the adult cohort (current/p
ast smokers). Tuberculin skin tests (TST) were positive (greater than
or equal to 10 mm) in 55/195 melt and 35/123 women for a total prevale
nce of 28.3%. No case of active tuberculosis (TB) was identified by ei
ther chest X-ray (CXR) or sputum cultures (in selected cases). In cont
rast to. adult farm workers, who were predominantly born in Mexico (70
%), only 36% of adolescent workers (age 11-28 years, n = 107) were bor
n in Mexico with only 7.5% exhibiting TST positivity. Airflow obstruct
ion of large airways (5.8%) and small airways (12.9%) were also less c
ommon in adolescents than adults. In summary these studies document re
spiratory dysfunction in Hispanic migrant farm workers in Indiana and
highlight the need to closely monitor the respiratory health of this h
igh-risk population. (C) 1996 Wiley-Liss, Inc.