CONFORMATIONAL STUDIES OF STERICALLY COMPARABLE 2,4-DISUBSTITUTED BICYCLO[3.3.1]NONAN-9-ONE SYSTEMS .2.

Authors
RAVISHANKAR L KORDE SS TRIVEDI GK
Citation
L. Ravishankar et al., CONFORMATIONAL STUDIES OF STERICALLY COMPARABLE 2,4-DISUBSTITUTED BICYCLO[3.3.1]NONAN-9-ONE SYSTEMS .2., Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 35(1), 1996, pp. 1-4
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
35
Issue
1
Year of publication
1996
Pages
1 - 4
Database
ISI
SICI code
0376-4699(1996)35:1<1:CSOSC2>2.0.ZU;2-H
Abstract
Condensation of cyclohexanone with cinnamaldehyde and morpholine in th e presence of anhydrous CeCl3 results in the formation of two isomers of 2-morpholino-4-phenylbicyclo[3.3.1]nonan-9-one, besides two other p roducts. The stereochemistry of the minor isomer has been determined w ith the help of H-1 NMR, COSY, C-13 NMR techniques and H-1 shift reage nt studies on sterically comparable 2,4-diphenyl-bicyclo[3.3.1]nonan-9 -one. In this case the molecule exists in a twin-chair conformation wi th the two substituents diequatorially oriented.