Hw. Hethcote et P. Vandendriessche, AN SIS EPIDEMIC MODEL WITH VARIABLE POPULATION-SIZE AND A DELAY, Journal of mathematical biology, 34(2), 1995, pp. 177-194
The SIS epidemiological model has births, natural deaths, disease-rela
ted deaths and a delay corresponding to the infectious period. The thr
esholds for persistence, equilibria and stability are determined. The
persistence of the disease combined with the disease-related deaths ca
n cause the population size to decrease to zero, to remain finite, or
to grow exponentially with a smaller growth rate constant. For some pa
rameter values, the endemic infective-fraction equilibrium is asymptot
ically stable, but for other parameter values, it is unstable and a su
rrounding periodic solution appears by Hopf bifurcation.