Aa. Weiss et Da. Owen, COLONIC DIAPHRAGM DISEASE IN A PATIENT RECEIVING LONG-TERM DICLOFENACTHERAPY, Canadian journal of gastroenterology, 9(7), 1995, pp. 413-416
A 65-year-old woman who had been taking diclofenac for five years deve
loped cramping central abdominal pain. Barium enema examination was ne
gative, but colonoscopy revealed prominent mucosal folds in the right
colon with areas of ulceration. Because of continued symptoms, a right
hemicolectomy was performed, which showed four separate short segment
strictures or diaphragms. This case demonstrates a rare complication
of nonsteroidal anti-inflammatory agent therapy that should be conside
red in the differential diagnosis of unexplained abdominal pain.