ANALYSIS OF THE 5'-END OF THE RAT PLASMA-MEMBRANE CA2-ATPASE ISOFORM-3 GENE AND IDENTIFICATION OF EXTENSIVE TRINUCLEOTIDE REPEAT SEQUENCES IN THE 5'-UNTRANSLATED REGION()

Authors
BURK SE MENON AG SHULL GE
Citation
Se. Burk et al., ANALYSIS OF THE 5'-END OF THE RAT PLASMA-MEMBRANE CA2-ATPASE ISOFORM-3 GENE AND IDENTIFICATION OF EXTENSIVE TRINUCLEOTIDE REPEAT SEQUENCES IN THE 5'-UNTRANSLATED REGION(), Biochimica et biophysica acta. Biomembranes, 1240(2), 1995, pp. 119-124
Citations number
33
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta. Biomembranes → ACNP
ISSN journal
00052736
Volume
1240
Issue
2
Year of publication
1995
Pages
119 - 124
Database
ISI
SICI code
0005-2736(1995)1240:2<119:AOT5OT>2.0.ZU;2-Y
Abstract
We have characterized the 5' end of the rat gene encoding isoform 3 of the plasma membrane Ca2+-ATPase using S1 nuclease protection and DNA sequence analysis. The 5'-untranslated region consists of over 900 nuc leotides and includes a 217-nucleotide sequence composed of alternatin g tracts of TCC and ACC trinucleotides. Analysis of genomic sequences 5' to the transcription initiation site revealed potential binding sit es for transcription factors that are active in muscle and brain.