Purpose: To report the findings concerning three patients with endopht
halmitis and one with panophthalmitis and orbital cellulitis radial ke
ratotomy surgery. Methods: One man referred with panophthalmitis and o
rbital cellulitis and three women referred with endophthalmitis were t
reated. Results: After radial keratotomy surgery, during which no micr
operforation or macroperforation had been reported, a severe Pseudomon
as panophthalmitis and orbital cellulitis developed in the man. All vi
sion was lost in that eye. Staphylococcus epidermidis endophthalmitis
developed in one woman, Streptococcus pneumoniae endophthalmitis in th
e second woman and Pseudomonas endophthalmitis in the third woman, aft
er undergoing radial keratotomy procedures during which microperforati
ons occurred. In the latter patient, bilateral simultaneous surgery wa
s performed, but only one eye became infected. The latter two infectio
ns resulted in light perception and hand motion vision respectively, I
n three cases, an initial keratitis was located in the inferior cornea
. Conclusions: Severe bacterial endophthalmitis can occur after radial
keratotomy surgery, even in the absence of microperforation during th
e procedure. Any evidence of postoperative keratitis must be regarded
seriously and treated aggressively. Despite use of this approach, the
effect on final visual acuity can be devastating.