THE EFFECT OF ACETIC-ACID AND SPECIFIC GROWTH-RATE ON ACETIC-ACID TOLERANCE AND TREHALOSE CONTENT OF SACCHAROMYCES-CEREVISIAE

The effects of acetic acid and specific growth rate on acetic acid tol erance and trehalose content of Saccharomyces cerevisiae CBS 2806 were studied using anaerobic chemostat cultures. Cells grown in the presen ce of acetic acid at a defined specific growth rate showed a higher ac etic acid tolerance and a slightly lower trehalose content. Cells grow n at a low specific growth rate showed a lower energy demand, a higher acetic acid tolerance, and a higher trehalose content. These results indicate that trehalose plays a growth rate dependent role in the tole rance of S. cerevisiae to acetic acid.