Objective-To examine trends in alcohol-related mortality before and af
ter the 1988 amendments to the Licensing Act in England & Wales. Desig
n-A population-based study where the population of England & Wales was
'exposed' to a change in licensing law and the population of Scotland
was 'unexposed'. Setting-Great Britain. Mortality data for England &
Wales were collected for five ICD categories of alcohol-related illnes
s over twelve years (1980-1991) and compared with control data obtaine
d from Scotland. Results-Mortality rates from chronic liver disease an
d cirrhosis (ICD 571), pancreatitis (ICD 577) and alcohol dependence o
r psychosis (ICD 303 & ICD 291) appeared to be unaffected by the exten
sion of opening hours. Deaths from alcoholic poisoning (ICD E860) in E
ngland & Wales increased slightly after 1988, but this coincided with
a large decrease in Scottish figures, and is therefore difficult to in
terpret unequivocally. Conclusion-Overall, there was no clear evidence
of a significant increase in alcohol-related mortality following intr
oduction of the new licensing laws, but more definitive conclusions ma
y be drawn following further experience and research.