Enantioselective catalytic trimethylsilylcyanations of aldehydes with
48% to 92% e.e. have been studied using the novel Ti-chiral Schiff bas
e complexes. We have found that the catalyst led to high enantoselecti
vity when the molar ratio of the Schiff base 1 to Ti(O-i-Pr)(4) was 2:
1.