CONVENIENT RESOLUTION OF (+ -)-PIPERIDINE-2-CARBOXYLIC ACID ((+/-)-PIPECOLIC ACID) BY SEPARATION OF PALLADIUM(II) DIASTEREOMERS CONTAINING ORTHOMETALLATED (S)-(-)-1-[1-(DIMETHYLAMINO)ETHYL]NAPHTHALENE/

Authors
HOCKLESS DCR MAYADUNNE RC WILD SB
Citation
Dcr. Hockless et al., CONVENIENT RESOLUTION OF (+ -)-PIPERIDINE-2-CARBOXYLIC ACID ((+/-)-PIPECOLIC ACID) BY SEPARATION OF PALLADIUM(II) DIASTEREOMERS CONTAINING ORTHOMETALLATED (S)-(-)-1-[1-(DIMETHYLAMINO)ETHYL]NAPHTHALENE/, Tetrahedron : asymmetry, 6(12), 1995, pp. 3031-3037
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
6
Issue
12
Year of publication
1995
Pages
3031 - 3037
Database
ISI
SICI code
0957-4166(1995)6:12<3031:CRO(-A>2.0.ZU;2-6
Abstract
(+/-)-Piperidine-2-carboxylic acid ((+/-)-pipecolic acid) has been res olved by the fractional crystallisation of diastereomeric palladium(II ) complexes containing orthometallated (S)-(-)-1-[1-dimethylamino)ethy l]naphthalene. The enantiomers of the acid were liberated from the ind ividual configurationally homogeneous diastereomers of the complex in high yield with [alpha](D)+/-26.0 (c 1.00, H2O). The crystal and molec ular structures of both diastereomers of the complex have been determi ned.