LINKAGE ANALYSIS, A PRIMER FOR DERMATOLOGISTS

Citation
Sl. Debie et Am. Depaepe, LINKAGE ANALYSIS, A PRIMER FOR DERMATOLOGISTS, EJD. European journal of dermatology, 5(8), 1995, pp. 653-658
Citations number
43
Categorie Soggetti
Dermatology & Venereal Diseases
ISSN journal
11671122
Volume
5
Issue
8
Year of publication
1995
Pages
653 - 658
Database
ISI
SICI code
1167-1122(1995)5:8<653:LAAPFD>2.0.ZU;2-E
Abstract
The enormous progress in molecular biology has created powerful means and techniques for the analysis of the human genome. These tools inclu de a generation of DNA markers which increase the potential applicatio ns of linkage analysis in medical genetics, not only a a research tool , but also in the management of families with hereditary disease. Basi c terminology and principles are explained and some applications in th e field of dermatology are presented.