POROKERATOTIC ECCRINE OSTIAL AND DERMAL DUCT NEVUS IN AN HIV-INFECTEDPATIENT

Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare disorder characterized by pits and keratotic papules appearing usually at birth. Histologically, PEODDN is characterized by parakeratotic co rnoid lamellae in the eccrine ducts. We present here a case of the sys tematized form of PEODDN in a 23-year-old man with human immunodeficie ncy virus (HIV) infection. The patient had a 2-month history of kerato tic and verrucous papules and nodules, distributed over all extremitie s; a group of punctate pits were present on the soles. PEODDN adds to pulosquamous dermatoses that develop in HIV-positive patients in assoc iation with a marked immunosuppression. Immunosuppression could act as trigger factor and precipitate the onset or the exacerbation of these porokeratotic hamartomatous lesions thus explaining the unusual clini cal features and the extensive involvement observed in our patient.