DAMAGE OF CATECHOLAMINERGIC SYSTEM IN RAT S CAUSES DECELERATION OF EARLY BEHAVIORAL-PATTERNS

Authors
PODKLETNOVA IM ALKHO HE
Citation
Im. Podkletnova et He. Alkho, DAMAGE OF CATECHOLAMINERGIC SYSTEM IN RAT S CAUSES DECELERATION OF EARLY BEHAVIORAL-PATTERNS, Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova, 45(5), 1995, pp. 1023-1028
Citations number
12
Categorie Soggetti
Physiology,Neurosciences
Journal title
Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova → ACNP
ISSN journal
00444677
Volume
45
Issue
5
Year of publication
1995
Pages
1023 - 1028
Database
ISI
SICI code
0044-4677(1995)45:5<1023:DOCSIR>2.0.ZU;2-Y
Abstract
Influence of 6-hydroxydopamine (6-OHDA) on catecholaminergic brain sys tem and development of early behavioural patterns was studied in 1-20- days-old Wistar rats. after 6-OHDA neonatal injection the number on ca techolaminergic terminals in deep layers of pons-medulla was considera bly reduced while the number of catecholaminergic neurons was 2-3 time s increased. Damage of catecholaminergic innervation of the forebrain of rats was shown to cause a delay in development of washing behaviour , searching activity and disturbance of orientation in new environment .