PLATINUM METAL-COMPLEXES WITH SOME NEW BIFUNCTIONAL LIGANDS .1. PYRAZOLE AMIDE COMPLEXES WITH PD-II AND PT-II

The pyrazolyl group has been used in conjuction with the amido group f or the design and synthesis of a new series of bifunctional ligands, P 2CH2C(O)NHR, where Pz = 1-pyrazolyl/3,5-dimethyl-1-pyrazolyl; R=H(APz/ ADMPz), Me(MAPz/MADMPz), Ph(PAPz/PADMPz). These ligands have been char acterized based on their mass, IR, H-1 and C-13{H} NMR spectra and the ir complexes with Pd-II and Pt-II reported. Simple mixing of aqueous s olutions of K-2[MCl(4)] (M = Pd, Pt) and the pyrazole amide in a 1:2 r atio gave neutral complexes of the type cis-MCl(2)L(2). Alternatively, an aqueous solution of K-2[MCl(4)] added to an aqueous solution of li gand at pH similar to 8.0 afforded neutral bis-chelates of the type ML (2). A neutral monodentate coordination (LH) has been assigned for the ligand in the former complexes, whereas uninegative bidentate coordin ation through deprotonated amide nitrogen has been assigned in the lat ter complexes.