SYNTHESIS AND CHARACTERIZATION OF A WATER-SOLUBLE METALLOPEPTIDE THATRESEMBLES A PARALLEL BETA-PLEATED SHEET

Authors
OGAWA MY GRETCHIKHINE AB SONI SD DAVIS SM
Citation
My. Ogawa et al., SYNTHESIS AND CHARACTERIZATION OF A WATER-SOLUBLE METALLOPEPTIDE THATRESEMBLES A PARALLEL BETA-PLEATED SHEET, Inorganic chemistry, 34(26), 1995, pp. 6423
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Inorganic chemistry → ACNP
ISSN journal
00201669
Volume
34
Issue
26
Year of publication
1995
Database
ISI
SICI code
0020-1669(1995)34:26<6423:SACOAW>2.0.ZU;2-V
Abstract
The title metallopeptide consists of two divalinyl peptides attached t o the carboxylate groups of the ruthenium polypyridyl complex. [Ru(bpy )(2)L](2+): bpy = 2,2'-bipyridine; L = 3,5-dicarboxy-2,2'-bipyridine. The charged ruthenium complex is water soluble and is shown by variabl e temperature, and 2-D NMR to consist a parallel arrangement of intera cting, extended peptide strands that ir reminiscent of the beta-sheet structure. Circular dichroism results support this assignment.