A SIMPLE CONVERSION OF THIAZOLO[2,3-B]QUINAZOLINONES AND [1,3]THIAZINO[2,3-B]QUINAZOLINONES AND ANALOGOUS FUSED THIENO[2,3-D]PYRIMIDINONES INTO HETEROCYCLIC SUBSTITUTED ALKYL DISULFIDES

A facile conversion of 5H-thiazolo[2,3-b]quinazolin-5-one (la), 6H-3,4 -dihydro[1,3]thiazino[2,3-b]quinazolin-6-one (1b), as well as analogou s fused thieno[2,3-d]pyrimidinones 2a, b into heterocyclic substituted alkyl disulfides 3a-d, 4a-d is reported, The conversion was performed by ring cleavage with sodium methoxide or sodium ethoxide followed by intermolecular oxidative trapping.