Study objective - To compare the rates of reported emergency appendice
ctomies in a cohort study of vegetarians and nonvegetarians by partici
pants' history of meat consumption. Design - This was a prospective co
hort study in which participants were asked about their lifetime histo
ry of meat consumption/avoidance and, separately, whether they had had
an appendicectomy. Appendicectomy was described as either ''emergency
'' or ''non-emergency'' according to details supplied by the participa
nt. Setting - The United Kingdom. Participants - These comprised more
than 11000 people, of whom 4852 (44%) completed both an appendicectomy
form and a dietary questionnaire giving details of their lifetime his
tory of meat consumption. Main results - The percentage who reported a
n emergency appendicectomy was higher among lifelong meat eaters (10.7
%) than either lifelong non-meat eaters (7.8%) or those who had stoppe
d eating meat (8.0%); and the operations were performed at an earlier
age in this first group (mean values 18.9, 26.0, and 19.6 years respec
tively). The overall age adjusted emergency appendicectomy rate ratio
comparing participants who did not eat meat with those who ate meat wa
s 0.47 (95% confidence interval 0.35, 0.65). Conclusions - The results
suggest that people who do not eat meat have a 50% lower risk of requ
iring an emergency appendicectomy than those who do. The data do not,
however, allow the reliable testing of other hypotheses, so meat consu
mption may simply be a marker for another dietary, lifestyle, or socio
economic factor.